The Single Best Strategy To Use For modafinil norge
The Single Best Strategy To Use For modafinil norge
Blog Article
apalutamide will decrease the extent or effect of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration of apalutamide, a solid CYP3A4 inducer, with medications which can be CYP3A4 substrates may result in lower exposure to these medications.
Allergic reactions such as rash, angioedema, anaphylaxis, and Stevens–Johnson syndrome could seldom be brought on by an immunological reaction to modafinil or its metabolites.
C: Use with warning if Gains outweigh pitfalls. Animal studies display hazard and human research not obtainable or neither animal nor human studies finished.
Throw absent unused or expired medications. Never flush down a toilet or pour down a drain Except if you might be instructed to do so. Look at with your pharmacist For those who have questions about The obvious way to toss out drugs. There may be drug consider-again applications in your neighborhood.
Doses as much as four hundred mg/working day, given as just one dose, are already nicely tolerated, but there's no consistent proof this dose confers more advantage outside of that with the two hundred mg/working day dose
efavirenz will reduce the level or effect of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Discontinue interfering medicines for a minimum check here of five fifty percent-lives ahead of administration of either the dosimetry or an iobenguane dose. Will not administer these medications until no less than seven times immediately after Just about every iobenguane dose.
Modafinil will not likely get rid of obstructive rest apnea or take care of its underlying will cause. Comply with your health care provider's Recommendations about all your other treatments for this disorder.
modafinil will improve the amount or impact of lansoprazole by impacting hepatic enzyme CYP2C19 metabolism. Insignificant/Significance Not known. Web impact on pantoprazole actions unfamiliar on account of opposing consequences of CYP450 enzymes; monitor
Modafinil is likewise accessible to astronauts aboard the International Room Station for that administration of fatigue due to circadian dyssynchrony in orbit.[79]
Along with its essential effects, a medicine may well lead to some unwelcome effects. While not every one of these side effects may well come about, whenever they do arise They could want healthcare attention.
It is far from recognized whether this drugs will harm an unborn little one. Notify your doctor If you're pregnant or system to be Expecting.
Stiripentol is actually a CYP3A4 inhibitor and inducer. Check CYP3A4 substrates coadministered with stiripentol for greater or lowered consequences. CYP3A4 substrates may possibly call for dosage adjustment.
stiripentol will raise the amount or outcome of modafinil by influencing hepatic enzyme CYP2C19 metabolism. Modify Therapy/Monitor Carefully. Think about lowering the dose of CYP2C19 substrates, if adverse reactions are knowledgeable when administered concomitantly with stiripentol.